Retrospective study of 476 tibial plateau levelling osteotomy procedures

The Effect of Glucosamine and Chondroitin on Stressed Equine Cartilage Explants

Large animal - Cartilage - Equine

Effective prevention and treatment of osteoarthritis for horses is still needed. This research tests the ability of glucosamine and chondroitin sulfate (GLN/CS) to mitigate inflammatory and mechanical stress in vitro. In this study, GLN/CS mediate this effect by a decrease of the synthesis of nitric oxide (NO) and a decrease of proteoglycan release from the extracellular matrix in stressed cartilage explants. Explants were cultured with interleukin-1 (IL-1) + mechanical trauma with and without GLN/CS. NO and prostaglandin E2 were measured as indicators of an inflammatory response. ...

A Quantitative Review of the Equinalysis System for Equine Locomotion Analysis

Large animal - Gait analysis - Equine

Movement analysis techniques allow objective and quantitative assessment of kinematic gait analysis. Consistent repeatability of the kinematic data is essential for such assessments. This study investigated whether the repeatability of a standardized Equinalysis Elite gait analysis system is sufficient to allow its use in clinical evaluation of equine lameness with reliable documentation of individual locomotion patterns. The extent to which examinations on different days affected the results when a standardized protocol was used was investigated. ...

Effect of pilot hole diameter and tapping on insertion torque and axial pullout strength of 4.0-mm cancellous bone screws.

Small animal - Fracture Fixation and Implants

Objective-To evaluate the effects of pilot hole diameter and tapping on insertion torque and axial pullout strength of 4.0-mm cancellous bone screws in a synthetic canine cancellous bone substitute. Sample-75 synthetic cancellous bone blocks (15 blocks/group). Procedures-For groups 1 through 5, screw size-pilot hole diameter combinations were 3.5-2.5 mm (cortical screws), 4.0-2.5 mm, 4.0-2.5 mm, 4.0-2.0 mm, and 4.0-2.0 mm, respectively. Holes were tapped in groups 1, 2, and 4 only (tap diameter, 3.5, 4.0, and 4.0 mm, respectively). ...

Evaluation of two sedation protocols for use before diagnostic intra-articular anaesthesia in lame dogs.

Small animal - Pain Management

Objectives: To assess the influence of two sedation protocols on the degree of lameness in dogs. Methods: Fifty lame dogs were allocated to one of two sedation protocols. Group ACPM (acepromazine + methadone; n=25) was sedated with acepromazine and methadone. Group MED (medetomidine antagonised with atipamezole; n=25) was sedated with medetomidine and reversed with atipamezole. Each dog was evaluated for lameness before and after sedation using videotapes. Four experienced clinicians allocated global lameness scores before and after sedation to each dog using a numerical rating scale. ...