Lorenzo D'Arpe, Daniele Bernardini Veterinary Clinics of North America Equine Practice August 2010 26 2 339-359 Clinical diagnostic venography allows in vivo visualization of the digital venous system and the effects of venocompression related to foot load and laminitis pathology. Venography has predictive potential and helps the clinician anticipate and treat laminitis tissue damage before it is detectable by plain radiography. The authors describe the podiatry radiographic technique to correctly perform digital venography and the modifications they have developed. The authors provide guidelines for the interpretation of laminitis venograms in the context of laminitis chronology. Frequent venographic monitoring of laminitis helps clinicians understand the sometimes puzzling chronology of the disease process and improves therapeutic outcome.